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Red wine might protect against lung cancer
Source: (American Association of Cancer Research)
Wednesday, October 08, 2008


PHILADELPHIA – Oct. 8, 2008 – Moderate consumption of red wine may lower the risk of lung cancer in men, according to a report in the October issue of Cancer Epidemiology, Biomarkers & Prevention; a journal of the American Association for Cancer Research.

Led by Dr. Chun Chao, a research scientist at Kaiser Permanente Department of Research and Evaluation, researchers measured the effect of beer, red wine, white wine and liquor consumption on the risk of lung cancer. After making adjustments for age, race/ethnicity, education, income, body mass index, history of chronic obstructive pulmonary disease or emphysema, and smoking history, they concluded that red wine was most strongly linked to a lower lung cancer risk.

"An antioxidant component in red wine may be protective of lung cancer, particularly among smokers," said Chun Chao.

The researchers collected data through the California Men's Health Study, which linked clinical data from California's health system with self-reported data from 84,170 men aged 45 to 69 years. Researchers obtained demographics and lifestyle data from surveys computed between 2000 and 2003, and identified 210 cases of lung cancer.

Among the study participants, there was on average a two percent lower lung cancer risk associated with each glass of red wine consumed per month. The most substantial risk reduction was among smokers who drank one to two glasses of red wine per day. The researchers reported a 60 percent reduced lung cancer risk in these men. Researchers warned men to stop smoking as the best way to reduce lung cancer risk noting that even men who drank one to two glasses of red wine per day still face higher lung cancer risk than do non-smokers.

No clear associations with lung cancer were noted for consumption of white wine, beer, or liquor. "Red wine is known to contain high levels of antioxidants. There is a compound called resveratrol that is very rich in red wine because it is derived from the grape skin. This compound has shown significant health benefits in preclinical studies," Chao said.

Chao said their findings should not be construed to recommend heavy alcohol consumption.

SOURCE: press material provided by the American Association for Cancer Research re: Alcoholic Beverage Intake and Risk of Lung Cancer: The California Men's Health Study: Cancer Epidemiol Biomarkers Oct 1 2008; 17 (10)

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