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CAL-101 Blocks Survival of CLL Cells By Targeting the Delta Isoform of the PI3 Kinase
Researchers at the Ohio State University have identified an experimental agent that targets chronic lymphocytic leukemia and perhaps other proliferative disorders of lymphocytes.
ARIAD Pharmaceuticals Announces Initiation of PACE (Ponatinib Ph+ ALL and CML Evaluation) Pivotal Trial in Drug-Resistant or Intolerant Chronic Myeloid Leukemia
Registration trial for approval of ponatinib in CML ARIAD Pharmaceuticals, Inc. announced the initiation of the pivotal Phase 2 clinical trial of its investigational pan-BCR-ABL inhibitor, ponatinib.
Exosomal Release Of Beta-Catenin May Explain Why CD82 And CD9 Suppress Tumor Metastasis
Researchers reveal a new way in which cells restrain beta-catenin and potentially suppress tumor metastasis: the protein can be ejected from cells in small vesicles called exosomes.
S-PAC-1 Targeting Cellular Enzyme Procaspase-3 Shows Promise in Canine Lymphoma, Providing Optimizism for Effects in Humans
Researchers have identified a new target for the treatment of lymphoma and are testing a potential new drug in pet dogs afflicted with the disease.
Personalized Medicine: Molecular Imaging Predicts Treatment Success in Many Cancers
A series of studies published in the September Journal of Nuclear Medicine (JNM) show that molecular imaging plays a critical role in the evaluation and treatment planning for a broad spectrum of cancers, including thyroid cancer and lymphoma.
Diverse Diet of Vegetables May Decrease Lung Cancer Risk
Adding a variety of vegetables to one’s diet may help decrease the chance of getting lung cancer, and adding a variety of fruits and vegetables may decrease the risk of squamous cell lung cancer, especially among smokers.
Copenhagen Researchers Activate Anti-Cancer Gene CDX2 in Colon Cancer Study
Researchers at the Faculty of Health Sciences at the University of Copenhagen have succeeded in decoding the genetic key that gives particular intestinal cells their identity.
Double-Therapy Approach Effectively Inhibited Brain Cancer Recurrence?
Researchers from the University of Massachusetts Medical School have identified a novel approach of combining chemotherapy with a targeted therapy to decrease the recurrence of glioblastoma multiforme, the most common and aggressive brain tumor.
Cost of Prostate Cancer Care Varies with Initial Treatment Choices
A new analysis has found that short-term and long-term costs of prostate cancer care vary considerably based on which treatment strategy a man initially receives.
Merrimack Pharmaceuticals and sanofi-aventis Initiate Enrollment in a Phase 2 Combination Study of MM-121 and exemestane in Breast Cancer
Merrimack Pharmaceuticals, Inc. and sanofi-aventis have announced that the first patient has received an initial dose in a Phase 2 randomized double blind clinical study combining MM-121 with exemestane (Aromasin®) in breast cancer patients.
Are new colon cancer drugs worth the cost?
ATLANTA – March 16, 2010 (cancerfacts.com) – One of the least discussed aspects of the current healthcare debate is the actual cost of treatments, and few studies ever include cost in the considerations of the benefits of those treatments.
Lung cancer drug fails to improve survival
NEW YORK – March 11, 2010 (cancerfacts.com) – Pfizer Inc. announced today it is suspending a large clinical trial of its lung-cancer drug.
Obesity linked to poor colon cancer prognosis
PHILADELPHIA – March 9, 2010 – Obese patients with colon cancer are at greater risk for death or recurrent disease compared to those who are within a normal weight range, according to a report in Clinical Cancer Research.
Colorectal drug fails to boost survival
LONDON – Mar. 8, 2010 – Anglo-Swedish pharmaceutical company, AstraZeneca, reported on Monday that its colorectal cancer drug failed to show that it is better than a competitor's drug.
New biomarkers for predicting the spread of colon cancer
HANGZHOU, China – Mar. 8, 2010 (cancerfacts.com)– Two proteins present in the blood of people with colon cancer may accurately serve as markers to predict whether the disease will spread, say scientists in China.
Common osteoporosis drugs may prevent breast cancer
SEATTLE – Mar. 2, 2010 (cancerfacts.com) – Women who take some types of drugs used to prevent and treat osteoporosis may be at lower risk of breast cancer, according to a new study.
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